XB-FEAT-29077542

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Revision as of 09:53, 6 February 2025 by Xenbase (talk | contribs) (Created page with "=''nek2''= This is the Xenbase wiki page for ''Xenopus nek2’’ genes. Please feel to record here any information that is not represented elsewhere on Xenbase. =nomenclature changes= 06FEB2025 RSCOM-691 Nomenclature for LOC100328980 and nek2 Can you please take a look at LOC100328980 (GeneID:100328980 , XB-GENE-29077543) and assign it appropriate nomenclature? Synteny and protein similarity to the human NP_002488.1 suggests that this is the ortholog of human NEK2....")
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nek2

This is the Xenbase wiki page for Xenopus nek2’’ genes. Please feel to record here any information that is not represented elsewhere on Xenbase.

nomenclature changes

06FEB2025

RSCOM-691 Nomenclature for LOC100328980 and nek2

Can you please take a look at LOC100328980 (GeneID:100328980 , XB-GENE-29077543) and assign it appropriate nomenclature? Synteny and protein similarity to the human NP_002488.1 suggests that this is the ortholog of human NEK2. Currently, GeneID: 407849 (nek2, XB-GENE-962774) shares the nek2 gene symbol. Can you look at both these loci and assign appropriate nomenclature?

XB response: XB-GENEPAGE-962773 has X. trop 407849 on Chr8, and X. laevis 379177 on Chr5S XB-GENEPAGE-29077542 has X. trop 100328980 LOC100328980 on Chr5

The genes on Chr5 appear to be the true NEK2 orthologs.

We have moved the X. laevis nek2.S gene to the same genepage as the X. trop gene and we have renamed GeneID: 407849 (XB-GENE-962774)as nek2l /nek2 -like as interim measure, and removed the NEK orthologs.

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