XB-FEAT-29089670
parp14l.2
nomenclature changes
21FEB2025 following review by David Webb at NCBI, RSCOM-838 XB-GENEPAGE-29091266 and XB-GENEPAGE-6458584 both named parp14.3, synteny for these genes and symbol clash with parp14 genes on Chr1, the following notes and changes have been made.
RSCOM-838 XB-GENEPAGE-29091266 and XB-GENEPAGE-6458584 both named parp14.3
2 Xenbase genepage's with identical parp14.3 symbols but distinct gene names:
XB-GENEPAGE-29091266/'protein mono-ADP-ribosyltransferase PARP14, gene 3' and XB-GENEPAGE-6458584/'poly (ADP-ribose) polymerase family, member 14, gene 3'.
XB-GENEPAGE-29091266 is on chr 9 and that block of parp14-like genes shares better synteny with the PARP14 genes of other tetrapods (see attached PARP14.docx) so I'd prefer to keep parp14.3 there.
XB-GENEPAGE-6458584 and the adjacent gene on chr 1 are also parp14-like but lack the shared synteny and may be a Xenopus-specific duplication/translocation.
Can you retain XB-GENEPAGE-29091266 as parp14.3 and name XB-GENEPAGE-6458584 something else?
XB-GENEPAGE-6458584, re: genes on chr1/1L, the protein is not characterized in EggNogg6.0 and thus has no identifiable homology group, so we have changed nomenclature to parp14l (gene1), and parp14l.2 to indicate the lack the shared synteny and that these genes may be/likely are a Xenopus-specific duplication/translocation.
XB-GENEPAGE-6458584, now has Xtrop XB-GENE-29089671 parp14l (gene ID: 105947701) and Xlaevis XB-GENE-29089672 parp14l.L (geneID: 108695267)
XB-GENEPAGE-29089670 now has Xtr.parp14l.2, geneID:105947701 and Xla.parp14l.2.L( geneID:108695267)