XB-FEAT-17329856

fcrl4

This is the community wiki page for the gene fcrl4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

summary from NCBi for human FCRL4

FCRL4 - Fc receptor like 4

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]