XB-FEAT-29097850

LOC116412020

This is the Xenbase wiki page for Xenopus LOC116412020 genes. Please feel free to record here and relevant information about LOC116412020 that is not recorded elsewhere on Xenbase.

nomenlcature updates

30MAR2026.

The gene name was changed from uncharacterised LOC116412020 to VWFD domain-containing protein like following the domain analysis shown on Uniprot for accession A0A8J1JWX9.

annotation notes

This is an extremely long protein, with many domains, 9 or which are conserved:

smart00216. Location:5826 → 5983

VWD; von Willebrand factor (vWF) type D domain smart00832. Location:6022 → 6091

C8; This domain contains 8 conserved cysteine residues PHA03247 Location:3928 → 4415

PHA03247; large tegument protein UL36; Provisional cl17735 Location:5766 → 5821

VWC; von Willebrand factor type C domain pfam00094 Location:5438 → 5589

VWD; von Willebrand factor type D domain pfam01826 Location:5711 → 5764

TIL; Trypsin Inhibitor like cysteine rich domain pfam17517 Location:146 → 437

IgGFc_binding; IgGFc binding protein cd19941 Location:6100 → 6153

TIL; trypsin inhibitor-like cysteine rich domain NF033804 Location:1683 → 1919

Streccoc_I_II; antigen I/II family LPXTG-anchored adhesin

This protein is 100% identical to two other X. tropicalis proteins which are named ( thus taking the same root for gene name and adding the like suffix seems appropriate):

VWFD domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 256aa

VWFD domain-containing protein Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 4731aa