XB-FEAT-492114

ido2

This is the community wiki page for the gene ido2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature updates

06MAY2026 Xenopus gene names and symbol has changed from ido1 indoleamine 2,3-dioxygenase 1, to ido2, indoleamine 2,3-dioxygenase 2 based on orthology prediction analsyis by NCBI.

Note that IDO1 and IDO2 are adjacent, duplicated genes on Chrom8 in human but Xenopus only has the single gene, ido2, on chr3/3L.

In humans, the enzymes encoded by IDO1 & IDO2 genes metabolize tryptophan in the kynurenine pathway.