XB-FEAT-29097022

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izumo1.2

This is the Xenbase wiki page for the izumo1.2 gene(s). You may record here any information relevant to these gene that is not representated elsewhere on Xenbase.


nomenclature updates

05OCT2026

Xenopus gene name changed from LOC116411086, uncharacterized LOC116411086 to izumo1.2, sperm-oocyte fusion 1 gene 2.

This gene seems to be a duplicate of izumo1 in X. tropcailis only.

biological function

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008].

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