5HT (seratonin)

Description

"Serotonin is a biochemical messenger and regulator, synthesized from the essential amino acid L-Tryptophan. Serotonin in the nervous system acts as a local transmitter at synapses, and as a paracrine or hormonal modulator of circuits upon diffusion, allowing a wide variety of "state-dependent" behavioral responses to different stimuli. Serotonin is widely distributed in the nervous system of vertebrates and invertebrates and some of its behavioral effects have been preserved along evolution. Such is the case of aggressive behavior and rhythmic motor patterns, including those responsible for feeding." Extract from Human Metabolome Database.

Seratonin structure, Photo from Sigma-Aldrich

• • Genes Affected
  • htr1a

Synonyms

Serotonin; 5-HYDROXYTRYPTAMINE; 3-(2-Aminoethyl)-1H-indol-5-ol; Enteramine; 50-67-9

Suppliers

• Sigma H9523

Usage Notes

1uM

References

• PubChem
• Kim et al., 1999
• Comparative Toxicogenomics Database

>593 references found in Xenopus literature using textpresso

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