XB-FEAT-5834988

acsl6

This is the community wiki page for the gene acsl6 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

06/19/2017 Human name has changed for Entrez Gene: 2182. From acyl-CoA synthetase long-chain family member 4 to acyl-CoA synthetase long chain family member 4 ( removed 1 hyphen)

recorded synonyms

acs2; facl6; lacs2; lacs5; lacs 6

summary from NCBI

The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]