XB-FEAT-5815507

b3gnt3

This is the community wiki page for the gene b3gnt3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

summary of human B3GNT3 from NCBI

This gene [in human] encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.