Barasertib: Difference between revisions

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*[http://www.xenbase.org/literature/article.do?method=display&articleId=53927 Hanley et al., 2017]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=53927 Hanley et al., 2017]


> 7 Xenbase articles contain a reference to Barasertib or AZD1152 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
> 8 Xenbase articles contain a reference to Barasertib or AZD1152 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]


*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Revision as of 08:20, 15 February 2018

Description

Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis.

Barasertib structure, image from PubChem

Alternative names

  • AZD1152
  • UNII-16XC2U7W8N

Suppliers

Usage Notes

References

> 8 Xenbase articles contain a reference to Barasertib or AZD1152 according to textpresso