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synonym: Demecolcine "Demecolcine is a colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division."

  • -Pubchem Description
Colcemide structure, photo from PubChem

Genes Affected


  • Molecular Probes

Usage Notes


>143 Xenbase articles contain a reference to colcemid according to textpresso