XB-FEAT-993117

mtor

This is the community wiki page for the gene mtor please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08/07/2017 Human name has changed for Entrez Gene: 2475. From mechanistic target of rapamycin to mechanistic target of rapamycin kinase.

summary from NCBI

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]