XB-FEAT-5791399

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frem1

This is the community wiki page for the gene frem1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08.23.2019

Human symbol has changed for genepage ID: 5791399 From frem1b to frem1

10/10/2019

gene symbol changed by KAB to frem1l (frem1-like) due to identification of a true frem1 orthologue on chromosome 1.

This genepage can still be linked to human FREM1, but it should not be renamed

11/29/2022

top BLASTp:Human search results for frem1l (XB-GENEPAGE-5791399) are FREM1 protein isoforms, supporting that frem1l is a FREM1 type gene despite not sharing synteny with human.

EggNOG orthology predicts similarity to other FREM1 genes, further supporting frem1l as a FREM1 type gene.

synteny

frem1 (XB-GENEPAGE-22169437; chr.1) shares synteny with human FREM1 whereas frem1l (XB-GENEPAGE-5791399; chr.4) does not.