XB-FEAT-1218174

hcn2

This is the community wiki page for the gene hcn2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

01/18/2015 Human name has changed for Entrez Gene: 610. From hyperpolarization activated cyclic nucleotide-gated potassium channel 2 to hyperpolarization activated cyclic nucleotide gated potassium channel 2 ( note removed hyphen)

05/29/2017 Human name has changed for Entrez Gene: 610. From hyperpolarization activated cyclic nucleotide gated potassium channel 2 to hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

summary

The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]