XB-FEAT-942248

hpgd

This is the community wiki page for the gene hpgd please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08/07/2017 Human name has changed for Entrez Gene: 3248. From hydroxyprostaglandin dehydrogenase 15-(NAD) to 15-hydroxyprostaglandin dehydrogenase

summary from NCBI

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]