XB-FEAT-6258052

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mad1l1

This is the community wiki page for the gene mad1l1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

09/24/2017 Human name has changed for Entrez Gene: 8379. From MAD1 mitotic arrest deficient like 1 to mitotic arrest deficient 1 like 1

summary from NCBI

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]