XB-FEAT-985840

cilk1

This is the community wiki page for the gene cilk1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

Undated

Human name has changed for Entrez Gene: 22858. From intestinal cell (MAK-like) kinase to intestinal cell kinase

10.18.2019

Xenopus symbol has changed for genepage ID: 985840 From ick to cilk1

Human symbol has changed for Entrez Gene: 22858. From ICK to CILK1

Human name has changed for Entrez Gene: 22858. From intestinal cell kinase to ciliogenesis associated kinase 1

Summary from NCBI for human CILK1

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]