XB-FEAT-5910007

chuk

This is the community wiki page for the gene chuk please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

05.13.19 Human name has changed for Entrez Gene: 1147. From conserved helix-loop-helix ubiquitous kinase to component of inhibitor of nuclear factor kappa B kinase complex

Summary from NCBI for human CHUK

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]