XB-FEAT-922295

kirrel3

This is the community wiki page for the gene kirrel3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

06/12/2017.

Human name has changed for Entrez Gene: 84623. From kin of IRRE like 3 (Drosophila) to kirre like nephrin family adhesion molecule 3.

summary from NCBI

The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]