XB-FEAT-5795058

ccdc115

This is the community wiki page for the gene ccdc115 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

24APRIL2023

Xenopus gene name updated from XB5795058 to ccdc115

Summary for human CCDC115 from NCBI

The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferation and suppresses cell death. Defects in this gene are a cause of congenital disorder of glycosylation, type IIo in humans. [provided by RefSeq, Mar 2016]