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"Lovastatin is a fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver." Source: MeSH

structure, image from PubChem

Alternative names

  • 75330-75-5
  • mevinolin
  • Mevacor
  • Lovalip

Usage Notes


> 65 Xenbase articles contain a reference to Lovastatin or Mevinolin according to textpresso