XB-FEAT-494798

macf1

This is the community wiki page for the gene macf1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

05.13.19 Human name has changed for Entrez Gene: 23499. From microtubule-actin crosslinking factor 1 to microtubule actin crosslinking factor 1

Summary from NCBI for human MACF1

This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]