XB-FEAT-481281

nherf2

This is the community wiki page for the gene nherf2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

04/22/2016 Human name has changed for Entrez Gene: 9351. From solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 to SLC9A3 regulator 2

2023/01/26

Human symbol has changed for genepage ID: 481281 From slc9a3r2 to NHERF2

Human name changed from SLC9A3 regulator 2 to NHERF family PDZ scaffold protein 2

summary for human NHERF2 from NCBI

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]