Nicorandil: Difference between revisions

Latest revision as of 13:09, 20 December 2017

Description

Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP.

nicorandil structure, photo from pubchem

Genes Affected

Suppliers

via pubChem
Merck KgaA

Usage Notes

4.7uM from stock of 100mg/11mL of water + 1 mL of DMSO

References

>19 Xenbase articles contain a reference to nicorandil according to textpresso

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@@ Line 1: / Line 1: @@
 ==Description==
-[[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]]
+Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP.
+[[File:nicorandil.png|frame|right|nicorandil structure, photo from pubchem]]
 ==Genes Affected==
 ==Suppliers==
-*[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENBASE]
+*[https://pubchem.ncbi.nlm.nih.gov/compound/47528#section=Chemical-Vendors via pubChem]
+*Merck KgaA
 ==Usage Notes==
+.7uM from stock of 100mg/11mL of water + 1 mL of DMSO
 ==References==
-*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]
+*[https://pubchem.ncbi.nlm.nih.gov/compound/47528 Pubchem]
-*[http://www.xenbase.org/literature/article.do?method=display&articleId=__________ ____ et al., 2xxxx]
+*[http://www.xenbase.org/literature/article.do?method=display&articleId=6115 Cheng et al., 2002]
->___ Xenbase articles contain a reference to _____ according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
+>19 Xenbase articles contain a reference to nicorandil according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
 *
 *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]