Nicorandil: Difference between revisions

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==Description==
==Description==
Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP.
[[File:nicorandil.png|frame|right|nicorandil structure, photo from pubchem]]
[[File:nicorandil.png|frame|right|nicorandil structure, photo from pubchem]]


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==Suppliers==
==Suppliers==
*[https://pubchem.ncbi.nlm.nih.gov/compound/47528#section=Chemical-Vendors via pubChem]
*[https://pubchem.ncbi.nlm.nih.gov/compound/47528#section=Chemical-Vendors via pubChem]
*[Merck KgaA]
*Merck KgaA


==Usage Notes==
==Usage Notes==

Latest revision as of 13:09, 20 December 2017

Description

Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP.

nicorandil structure, photo from pubchem

Genes Affected

Suppliers

Usage Notes

4.7uM from stock of 100mg/11mL of water + 1 mL of DMSO

References

>19 Xenbase articles contain a reference to nicorandil according to textpresso