PP2: Difference between revisions

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*[http://www.xenbase.org/literature/article.do?method=display&articleId=1490 Robles et al., 2005]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=1490 Robles et al., 2005]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=9003 Browaeys-Poly et al. 2001]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=9003 Browaeys-Poly et al. 2001]
*[http://www.xenbase.org/literature/article.do?articleId=50105&method=display Santiago-Medina, 2015]


>18 Xenbase articles contain a reference to PP2 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>18 Xenbase articles contain a reference to PP2 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 14:04, 19 May 2016

Description

Synonym: 4-Amino-3-(4-chlorophenyl)-1-(t-butyl)-1H-pyrazolo[3,4-d]pyrimidine, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, AG 1879

"PP2 is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2."

  • -Sigma Product Description
PP2 structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

1uM in cell culture media, up to 10mM in certain applications

References

>18 Xenbase articles contain a reference to PP2 according to textpresso