XB-FEAT-945185

pea15

This is the community wiki page for the gene pea15 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08/15/2017 Human name has changed for Entrez Gene: 8682. From phosphoprotein enriched in astrocytes 15 to proliferation and apoptosis adaptor protein 15

synonyms added: pea-15; hummat1h; ped-pea15

summary from NCBI

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]