XB-FEAT-5775923

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pitpnbl

This is the community wiki page for the gene pitpnbl please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.


nomenclature changes

25FEB2025

Following analysis of NCBIs RefSeq team (see RSCOM-706 Swap nomenclature of pitpnb (XB-GENE-5775924) and pitpnb.2 (XB-GENE-949250)) the gene name for Xenopus tropicalis GeneID:394727 (NP_989122.1) has changed from pitpnb to pitpnbl, in recognition the the true pitpnb gene, based on sequence similarity and synteny, is X. tropicalis GeneID: 780070 XB-GENE-949250.

X. laevis genes also updated.


Synteny 

GeneID:394727 (NP_989122.1) shares lesser sequence identity with human PITPNB and no synteny with it (see below):

tblastn of NP_989122.1 (GeneID:394727) to human genome (GRCh38p.14)- 87.76 % identity; 78% query cover; total score 405

tblastn of XP_031757844.1 (GeneID:780070) to human genome (GRCh38p.14)- 95.92 % identity; 89% query cover; total score 484

X. tropicalis pitpnb ([1])

>LOC101734336    >LOC101735172    <pitpnb (GeneID:394727)  <sult1b1    >LOC100493528

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