XB-FEAT-22061121 and XB-FEAT-6464257: Difference between pages

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imported>Xenbase
(Created page with "==otgl== This is the community wiki page for the gene "ogl" please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xen...")
 
imported>Xenbase
 
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==otgl==
=''nat8.5''=
This is the community wiki page for the gene "ogl" please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
This is the community wiki page for the gene ''nat8.5'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.


=nomenclature changes=
=nomenclature changes=
12.11.2018
NOV 2019


Human name has changed for Entrez Gene: 283310. From otogelin-like to otogelin like.
This gene represents one of 9 duplicated ‘nat8’ genes identified by Xenbase during analysis “Xenopus” v9/10 genome annotation, all on Chromosome 1 in “X. tropicalis” and “X. laevis”,  and is likely  a true ortholog of the human NAT8B gene.  


=Summary from NCBI=
Note that  not all duplications are present in “X. tropicalis”, and “X. laevis” does not always have both .L and .S homeologs.
 
The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012]

Revision as of 08:35, 30 June 2020

nat8.5

This is the community wiki page for the gene nat8.5 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

NOV 2019

This gene represents one of 9 duplicated ‘nat8’ genes identified by Xenbase during analysis “Xenopus” v9/10 genome annotation, all on Chromosome 1 in “X. tropicalis” and “X. laevis”, and is likely a true ortholog of the human NAT8B gene.

Note that not all duplications are present in “X. tropicalis”, and “X. laevis” does not always have both .L and .S homeologs.