XB-FEAT-6500120 and XB-FEAT-6464257: Difference between pages

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imported>Xenbase
(Created page with "=nomenclature changes= 08.23.2019 Human name has changed for Entrez Gene: 440093. From H3 histone family member 3C to H3.5 histone Human symbol has changed for genepage ID:...")
 
imported>Xenbase
 
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=''nat8.5''=
This is the community wiki page for the gene ''nat8.5'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
=nomenclature changes=
=nomenclature changes=
08.23.2019  
NOV 2019
Human name has changed for Entrez Gene: 440093. From H3 histone family member 3C to H3.5 histone
 
Human symbol has changed for genepage ID: 6500120 From h3f3c to h3-5
 
Human symbol has changed for Entrez Gene: 440093. From H3F3C to H3-5


=Summary from NCBI, human H3-5=
This gene represents one of 9 duplicated ‘nat8’ genes identified by Xenbase during analysis “Xenopus” v9/10 genome annotation, all on Chromosome 1 in “X. tropicalis” and “X. laevis”,  and is likely  a true ortholog of the human NAT8B gene.


Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. [provided by RefSeq, Oct 2015]
Note that not all duplications are present in “X. tropicalis”, and “X. laevis” does not always have both .L and .S homeologs.

Revision as of 08:35, 30 June 2020

nat8.5

This is the community wiki page for the gene nat8.5 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

NOV 2019

This gene represents one of 9 duplicated ‘nat8’ genes identified by Xenbase during analysis “Xenopus” v9/10 genome annotation, all on Chromosome 1 in “X. tropicalis” and “X. laevis”, and is likely a true ortholog of the human NAT8B gene.

Note that not all duplications are present in “X. tropicalis”, and “X. laevis” does not always have both .L and .S homeologs.