XB-FEAT-22172613: Difference between revisions
imported>Xenbase (Created page with "=b3galt2= This is the community wiki page for the gene ''b3galt2'' please feel free to add any information that is relevant to this gene that is not already captured elsewher...") |
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Based on synteny and reciprocal BALSTp matches to Human, this gene is now recognized as the true ''Xenopus'' orthologue of human B3GALT2. | Based on synteny and reciprocal BALSTp matches to Human, this gene is now recognized as the true ''Xenopus'' orthologue of human B3GALT2. | ||
In all gnathostomes,and in caecilians too, | In all gnathostomes, and in caecilians too, t'''he B3GALT2 gene sits inside an intron of CDC73''' on the opposite strand i.e., [ CDC73(...B3GALT2>)<...GLRX2>...RO60<...UCHL5> (for example, see Human GENEID:8707). | ||
Although the neighboring gene order is somewhat shuffled in the amphibians | |||
Although the neighboring gene order is somewhat shuffled in the amphibians ''Nanorana'' and ''Xenopus'', the ''b3galt2'' gene still sits '''inside''' of ''cdc73''. | |||
Consequently, Entrez GeneID:100380178 is now seen to be a '''like''' gene, one of up to nine different ''b3galt2-like'' genes downstream of ''ilf3'' on ''Xenopus'' chromosome 3. | Consequently, Entrez GeneID:100380178 is now seen to be a '''like''' gene, one of up to nine different ''b3galt2-like'' genes downstream of ''ilf3'' on ''Xenopus'' chromosome 3. | ||
David Webb notes that most reptiles, amphibians and basal mammals also have a few B3GALT2-like genes downstream of LIF3 gene ( e.g., see GeneID:115080934) but the genes seem to be frequently lost or unannotated. | David Webb notes that most reptiles, amphibians and basal mammals also have a few B3GALT2-like genes downstream of LIF3 gene ( e.g., see GeneID:115080934) but the genes seem to be frequently lost or unannotated. | ||
Revision as of 13:09, 13 January 2020
b3galt2
This is the community wiki page for the gene b3galt2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature updates
01.13.20
The identity of this gene and similar geens was assessed by David Webb from NCBI and Xenbase curators.
Based on synteny and reciprocal BALSTp matches to Human, this gene is now recognized as the true Xenopus orthologue of human B3GALT2.
In all gnathostomes, and in caecilians too, the B3GALT2 gene sits inside an intron of CDC73 on the opposite strand i.e., [ CDC73(...B3GALT2>)<...GLRX2>...RO60<...UCHL5> (for example, see Human GENEID:8707).
Although the neighboring gene order is somewhat shuffled in the amphibians Nanorana and Xenopus, the b3galt2 gene still sits inside of cdc73.
Consequently, Entrez GeneID:100380178 is now seen to be a like gene, one of up to nine different b3galt2-like genes downstream of ilf3 on Xenopus chromosome 3.
David Webb notes that most reptiles, amphibians and basal mammals also have a few B3GALT2-like genes downstream of LIF3 gene ( e.g., see GeneID:115080934) but the genes seem to be frequently lost or unannotated.