XB-FEAT-5885524

prss57

This is the community wiki page for the gene prss57 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

Summary from NCBI

This gene encodes an arginine-specific serine protease and member of the peptidase S1 family of proteins. The encoded protein may undergo proteolytic activation before storage in azurophil granules, in neutrophil cells of the immune system. Following neutrophil activation, the protease is released into the pericellular environment, where it may play a role in defense against microbial pathogens. [provided by RefSeq, Jul 2016]

Expression

in adult humans, expression restricted to bone marrow.

nomenclature changes

undated: Human symbol has changed for Entrez Gene: 400668 from prssl1 to prss57

01/22/2018 Human name has changed for Entrez Gene: 400668. From protease, serine 57 to serine protease 57