XB-FEAT-5839239

rad54b

This is the community wiki page for the gene rad54b please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

02/06/2018 Human name has changed for Entrez Gene: 25788. From RAD54 homolog B (S. cerevisiae) to RAD54 homolog B

Summary from NCBI

The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]