XB-FEAT-957567

bag1

This is the community wiki page for the gene bag1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

NCBI Summary for human BAG1

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]

nomenclature changes

10.18.2019

Human name has changed for Entrez Gene: 573. From BCL2 associated athanogene 1 to BAG cochaperone 1