Retinoic acid

Description

"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."

• -Sigma Product Description

Retinoic Acid structure, photo from Sigma-Aldrich

Genes Affected

• rara

Suppliers

• Sigma

References

• Pubchem
• Drysdale et al., 1991
• Nagy et al., 2015

>1484 Xenbase articles contain a reference to Retinoic Acid according to textpresso

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