SB431542: Difference between revisions

Latest revision as of 13:19, 9 April 2018

Description

"Potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. Suppresses TGF-β-induced proliferation of human osteosarcoma cells. Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells."

-Tocris Product Description

SB-431542 structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

References

> 40 Xenbase articles contain a reference to SB431542 according to textpresso

Back To Small Molecules Home Page

@@ Line 1: / Line 1: @@
 ==Description==
-[[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]]
+"Potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. Suppresses TGF-β-induced proliferation of human osteosarcoma cells. Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells."
+*-Tocris Product Description
-==Genes Affected==
-==Suppliers==
-*[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENBASE]
-==Usage Notes==
-==References==
-*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]
-*[http://www.xenbase.org/literature/article.do?method=display&articleId=__________ ____ et al., 2xxxx]
->___ Xenbase articles contain a reference to _____ according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
-*
-*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
+[[File:SB431542.png|frame|right|SB-431542 structure, photo from Sigma-Aldrich]]
 ==Genes Affected==
@@ Line 31: / Line 18: @@
 *[http://www.selleckchem.com/products/SB-431542.html Selleckchem]
-==references==
+==Usage Notes==
+==References==
 *[http://www.xenbase.org/literature/article.do?method=display&articleId=371 Ho et al., 2006]
-* >23 other references within Xenbase use SB-431542 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search Textpresso]
+*[http://www.xenbase.org/literature/article.do?method=display&articleId=49634 Chiu 2014]
+*[http://www.xenbase.org/literature/article.do?method=display&articleId=54570 Sato et al 2018]
+*[https://pubchem.ncbi.nlm.nih.gov/compound/4521392 NCBI PubChem CID:4521392]
+> 40 Xenbase articles contain a reference to SB431542 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
+*
+*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]