XB-FEAT-958428

sept6

This is the community wiki page for the gene sept6 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

05.13.19

Human symbol has changed for genepage ID: 958428 From sept6 to SEPTIN6

Human symbol has changed for Entrez Gene: 23157. From SEPT6 to SEPTIN6

Summary from NCBI for human

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]