XB-FEAT-6258977

trpc2

This is the community wiki page for the gene trpc2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

01/15/2018

Human name has changed for Entrez Gene: 7221. From transient receptor potential cation channel subfamily C member 2, pseudogene to transient receptor potential cation channel subfamily C member 2 (pseudogene)

08/19/2021

The human TRPC2 gene has been re-annotated after it was examined in more detail in vertebrates by the NCBI RefSeq team. They wrote: "In vertebrates we've overlooked annotating the XNDC1 gene upstream of TRPC2 due to over-extension of the TRPC2 CDS (PMID: 21854574). The over-extension of the TRPC2 CDS arose in part because these two genes are pseudogenized in human while readthrough transcription occurs in mouse. "

Thus the Xenopus gene name for trpc2 (which follows human) has been updated, removing the "pseudogene" from official name, as it is a functional gene in Xenopus. The gene symbol is unchanged.