XB-FEAT-5754212

gfus

This is the community wiki page for the gene gfus please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

2020/06/04

Human symbol has changed for genepage ID: 5754212 From tsta3 to gfus

Human name has changed for genepage ID: 5754212 from tissue specific transplantation antigen P35B to GDP-L-fucose synthase

summary for human GFUS from NCBI

Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]