XB-FEAT-962280

tub

This is the community wiki page for the gene tub please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

05.13.19

Human name has changed for Entrez Gene: 7275. From tubby bipartite transcription factor to TUB bipartite transcription factor

Summary from NCBI for human TUB

This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]