Valproic acid (VPA): Difference between revisions

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==References==
==References==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=55100 Rao and LaBonne 2018]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=55100 Rao and LaBonne 2018]
*[https://pubchem.ncbi.nlm.nih.gov/compound/5287620 NCBI PubChem CID:3121]
*[https://pubchem.ncbi.nlm.nih.gov/compound/3121 NCBI PubChem CID:3121]


> 84 Xenbase articles contain a reference to Valproic acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
> 84 Xenbase articles contain a reference to Valproic acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]

Latest revision as of 07:17, 25 October 2019

Description

"Valproic Acid is a synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. This agent's antitumor and antiangiogenesis activities may be related to the inhibition of histone deacetylases and nitric oxide synthase, which results in the inhibition of nitric oxide synthesis. (NCI04)" Source: NCIt


structure, image from PubChem

Alternative names

  • 2-Propylpentanoic acid
  • 99-66-1
  • Dipropylacetic acid
  • 2-Propylvaleric acid

Usage Notes

References

> 84 Xenbase articles contain a reference to Valproic acid according to textpresso