XB-FEAT-478209: Difference between revisions
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hnf1b and fzd4 have been identified as RA-induced genes responsible for pancreas specification. | hnf1b and fzd4 have been identified as RA-induced genes responsible for pancreas specification. | ||
=summary from NCBI= | |||
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008] | |||
Revision as of 03:44, 30 June 2017
fzd4
This is the community wiki page for the gene fzd4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
gene function and expression notes
source: Maja Gere and Tomas Pieler talk, EAC July 30th, 2017.
hnf1b and fzd4 have been identified as RA-induced genes responsible for pancreas specification.
summary from NCBI
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]