XB-FEAT-5764024

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plaat4

This is the community wiki page for the gene plaat4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

10.18.2019 Xenopus symbol has changed for genepage ID: 5764024 From rarres3 to plaat4

Human symbol has changed for Entrez Gene: 5920From rarres3 to PLAAT4 Human name has changed for Entrez Gene: 5920 From to retinoic acid receptor responder (tazarotene induced) 3 to phospholipase A and acyltransferase 4

Summary from NCBI for Human PLAAT4 (previous known as RARRES3)

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]