XB-FEAT-22172581: Difference between revisions

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Human name has changed for genepage ID: 22172581 From deltex 3, E3 ubiquitin ligase-like to deltex E3 ubiquitin ligase 3
Human name has changed for genepage ID: 22172581 From deltex 3, E3 ubiquitin ligase-like to deltex E3 ubiquitin ligase 3


8.19.2020: Sorry for any confusion- this gene is infact the dtx3-''like'' gene on Chromsome 8 in ''Xenopus'', in this gene order:  cd163> cd5l> cd163  '''dtx3-like'''<  LOC#(vm2r26)< LOC#(gprc6a) <
8.19.2020: This gene is in fact the dtx3-''like'' gene ''dtex3-like, deltex E3 ubiquitin ligase 3-like'' on Chromsome 8 in ''Xenopus''.


WARNING: there are 2 other ''deltex 3'' genes in human and Xenopus- ''dtx3'', and ''dtx3L''.  
In Xtrop geneome v9.1 it is found  in this gene order: cd163> cd5l> cd163 '''dtx3-like'''<  LOC#(vm2r26)< LOC#(gprc6a) <
 
In X. tropicalis v10.0 genome annotation , it is called LOC550107 and dtx3-like.1 in the lift over file. These are added as synonyms to this genepage.


The true ortholog of human DTX3 is ''Xenopus'' ''dtx3'' Gene ID: 2217250, on Chromosome 2, based on conserved gene order/synteny
We have removed ortholog links as these are yet to be confirmed.


The true ortholog of human DTX3L is ''Xenopus'' ''dtx3l'' Gene ID:100496352, based on conserved gene order/synteny,  is annotated on Scaffold 734 in Xtrop v9.1 () gene model '''gene26586''', and in ''X. laevis'' v9.2 is on Chr9-10 (dtx3l.L gene ID:108701239; dtx3l.S gene ID:108702882). Currently there is no Xenbase gene page for these genes, and the vertebrate orthologs need to be moved to the correct gene pages.  
WARNING: there are 2 other  ''deltex 3'' genes in human and Xenopus- ''dtx3'', and ''dtx3L''.  


Note that the L  human in the gene DTX3L, doesn't appear stand for 'like' as it would in a ''Xenopus'' gene name.
1) The true ortholog of human DTX3 is ''Xenopus'' ''dtx3'' Gene ID: 2217250, on Chromosome 2, based on conserved gene order/synteny


Following this analysis, we have reverted name for this gene to ''dtex3-like, deltex E3 ubiquitin ligase 3-like''.  
2) The true ortholog of human DTX3L is ''Xenopus'' ''dtx3l'' Gene ID:100496352, based on conserved gene order/synteny, which  is annotated on Scaffold_734 in Xtrop v9.1  (gene model '''gene26586''') and in ''X. laevis'' v9.2 is on Chr9_10 (dtx3l.L gene ID:108701239; dtx3l.S gene ID:108702882). A new genepage is being built on Xenbase for these genes, and the vertebrate orthologs will be moved to this new gene pages.  


Updated orthologs to human mouse fly and zebrafish: (coming soon)
Note that the 'L'  human in the gene DTX3L, doesn't appear stand for 'like' as it would in a ''Xenopus'' gene name.

Revision as of 14:43, 19 August 2020

dtx3-like

This is the community wiki page for the gene dtx3-like please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

1.3.2020 :gene page created for dtx3-like

6.30.20: Following Entrz report:

Human symbol has changed for genepage ID: 22172581 From dtx3-like to DTX3

Human name has changed for genepage ID: 22172581 From deltex 3, E3 ubiquitin ligase-like to deltex E3 ubiquitin ligase 3

8.19.2020: This gene is in fact the dtx3-like gene dtex3-like, deltex E3 ubiquitin ligase 3-like on Chromsome 8 in Xenopus.

In Xtrop geneome v9.1 it is found in this gene order: cd163> cd5l> cd163 dtx3-like< LOC#(vm2r26)< LOC#(gprc6a) <

In X. tropicalis v10.0 genome annotation , it is called LOC550107 and dtx3-like.1 in the lift over file. These are added as synonyms to this genepage.

We have removed ortholog links as these are yet to be confirmed.

WARNING: there are 2 other deltex 3 genes in human and Xenopus- dtx3, and dtx3L.

1) The true ortholog of human DTX3 is Xenopus dtx3 Gene ID: 2217250, on Chromosome 2, based on conserved gene order/synteny

2) The true ortholog of human DTX3L is Xenopus dtx3l Gene ID:100496352, based on conserved gene order/synteny, which is annotated on Scaffold_734 in Xtrop v9.1 (gene model gene26586) and in X. laevis v9.2 is on Chr9_10 (dtx3l.L gene ID:108701239; dtx3l.S gene ID:108702882). A new genepage is being built on Xenbase for these genes, and the vertebrate orthologs will be moved to this new gene pages.

Note that the 'L' human in the gene DTX3L, doesn't appear stand for 'like' as it would in a Xenopus gene name.