Y27632: Difference between revisions
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*[https://pubchem.ncbi.nlm.nih.gov/compound/448042 Pubchem] | *[https://pubchem.ncbi.nlm.nih.gov/compound/448042 Pubchem] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=44762 Langdon et al., 2012] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=44762 Langdon et al., 2012] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=41781 Zhou] | |||
>28 Xenbase articles contain a reference to Y27632 or Y-27632 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | >28 Xenbase articles contain a reference to Y27632 or Y-27632 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
* | * | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | ||
Revision as of 13:38, 6 July 2015
Description
"Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP."
- -Sigma Product Description
Genes Affected
Suppliers
Usage Notes
10uM in culture
References
>28 Xenbase articles contain a reference to Y27632 or Y-27632 according to textpresso