Y27632: Difference between revisions

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*[http://www.xenbase.org/literature/article.do?method=display&articleId=44762 Langdon et al., 2012]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=44762 Langdon et al., 2012]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=41781 Zhou]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=41781 Zhou]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=49645 Kim]


>28 Xenbase articles contain a reference to Y27632 or Y-27632 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>28 Xenbase articles contain a reference to Y27632 or Y-27632 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 07:46, 23 March 2016

Description

"Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP."

  • -Sigma Product Description
Y27632 structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

10uM in culture

References

>28 Xenbase articles contain a reference to Y27632 or Y-27632 according to textpresso