XB-FEAT-22065613

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sprtnl3

This is the community wiki page for the gene sprtnl.3, please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

05JAN2023

GENE NAME CHANGED FROM provisional ortholog of SprT-like N-terminal domain TO SprT-like N-terminal domain like gene 3

GENE SYMBOL CHANGED FROM XB22065613 [provisional:sprtn] TO sprtnl.3


Both gene name and symbol have been approved by HGNC & NCBI Ref Seq.

14JULY2023

Gene symbol changed from sprtnl.3 to sprtnl3 in accordance with Xenbase nomenclature guidelines.

synteny

X. laevis sprtn.S on Chromosome 5.S seems to be the true orthology of human SPRTN, with both being flanked by eglin1 and exoc8.

Human chr 1: RNA5SP80< ... EXOC8< ... SPRTN> ...LOC107985360> ... EGLN1< ...LOC122152336>

X. laevis chr5.S: sf3b5.S< ... exoc8.S< ...tsnax.S< ... egln1.S< .. sprtn.S> ... acta1.S< ... LOC108717893< ...


the 2 other X. tropicalis genes have been given provisional names sprtn like gene 2[geneID: 105945677) and sprtn like gene 3 [geneID: 105948375]

X. trop chr1: jsprp1> ...amh< ...sf3a2< ... plekhj1> ... dot1l> ... 'sprtnl2'> ... ap3d1> ... mob3a> ... mknk2> ... btbd2> ... csnk1g2< ...

X. trop chr9: gng13> ... chtf18< ... rpusd1> ... msin< ... 'sprtnl3'< ... LOC#3326> ... LOC#3470 ...