XB-FEAT-22169518

wadc8l

This is the community page for the Xenopus gene wadc8l. Please feel free to add any relevant information here regarding this gene that is not represented elsewhere on Xenbase.

nomenclature changes

04JAN2023

This gene was given the gene symbol wfdc8l following the Xenopus nomeclature guidelines, based on the root synbol for the human WAP four-disulfide core domain 8 gene, which is is WFDC8, with the suffix 'l' which stands for 'like'.

XB22169518 is recored as a legacy symbol.

summary for the human WFDC8 gene from NCBI

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to Human chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this Human gene, and they encode the same protein. [provided by RefSeq, Jul 2008]