XB-FEAT-961599

mal2

This is the community wiki page for the gene mal2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

12.13.2017

Human name has changed for Entrez Gene: 114569. From mal, T-cell differentiation protein 2 (gene/pseudogene) to mal, T cell differentiation protein 2 (gene/pseudogene)

3/4/2022

removed ‘pseudogene’ from gene name as human gene ( reviewed) is status’ protein coding’

summary of human MAL2 from NCBI

This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008]