XB-FEAT-1000859

senp7

This is the community wiki page for the gene senp7 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

03.12.18 Human name has changed for Entrez Gene: 57337. From SUMO1/sentrin specific peptidase 7 to SUMO specific peptidase 7

Summary from NCBI

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]